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AP-1 overexpression impairs corticosteroid inhibition of collagen production by fibroblasts isolated from asthmatic subjects
From: Asthma News
This study determined the effect of dexamethasone (Dex) on collagen production by bronchial fibroblasts derived from asthmatic and healthy subjects. Expression of procollagen mRNA in fibroblasts from asthmatics and normal controls was determined by quantitative PCR. Regulation of the procollagen-1I promoter was evaluated by transient transfections. Transforming growth factor-β (TGF-β) protein expression was determined by [...]
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Roles of epithelial cell-derived periostin in TGF-{beta} activation, collagen production, and collagen gel elasticity in asthma [Cell_Biology]
Periostin is considered to be a matricellular protein with expression typically confined to cells of mesenchymal origin. Here, by using… (Source: Proceedings of the National Academy of Sciences) MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
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The best asthmatic you can be
After reviewing my past writings, I wrote a post a while back called, "Being the Best Asthmatic you can be." I've decided that this ought to be an asthma type. Sure you have Gallant Asthmatics -- who are prefect. Sure you have Goofus Asthmatics who are flawed in every sense of the word. Yet what of the rest of us who are normal? We ought to have an asthma classification of our own. Hence, the Adept Asthmatic. This is the more realistic asthma type. They strive to be the best they can be, although they are not perfect because, if you think about it, perfection is not achievable. Normal asthmatics will miss an occasional dose of medicine, and will take an occasional extra puff on their inhaler, and may even use their rescue inhaler without a spacer. Yet they are also not complete...
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Anti-asthmatic activities in mycelial extract and culture filtrate of Cordyceps sphecocephala J201.
This study investigated the effects of mycelial extract and culture filtrate of Cordyceps sphecocephala J201 on airway hyper-responsiveness, pulmonary immune cell infiltration, and Th2 cytokine expression in animal models of asthma. After Concanavalin A (Con A) activation of mouse primary spleen cells, the IL-4 and IL-13 cytokine expression were significantly decreased in the presence of [...]
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FEV25-75 identifies airflow dysfunction in asthmatic children with normal FEV1
Assessment of forced expiratory flow at between 25% and 75% of vital capacity may help identify airflow obstruction in asthmatic children with normal FEV1 values, say researchers. (Source: MedWire News - Respiratory) MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
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Choosing A Diamond Ring
The cut of a diamond is the most important factor to consider when determining which diamond ring to buy. The rating of a diamond’s cut will determine the best bargain, when you are looking at two comparatively priced diamonds. The ability of a diamond to reflect and refract light, making it sparkle, is determined by [...]
More | Asthma, Health, & Technology
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